摘要
术前放化疗联合全系膜切除手术为局部晚期直肠癌患者治疗的标准模式,术前放化疗比术后放化疗提高了肿瘤降期率、保肛率及局部控制率,术前放化疗后达到病理完全缓解患者拥有更好的预后。本文就近年来术前放化疗的研究进展作一综述。
Preoperative neoadjuvant chemoradiotherapy(NCR)combined with total mesorectal excision(TME)is the standard treatment mode for locally advanced rectal cancer.Compared with postoperative NCR,preoperative NCR increases the tumor down-staging,sphincter-preserving rate and local control rate.Patients who attain pathological complete response(pCR)after preoperative NCR have better prognosis compared with their counterparts.This article reviews the research progress on preoperative NCR in recent years.
作者
王奕如
张勇
吴童
沈梅竹
Wang Yiru;Zhang Yong;Wu Tong;Shen Meizhu(Department of Radiation Oncology,First Affiliated Hospital of Guangxi Medical University,Radiation Oncology Clinical Medical Research Center of Guangxi,Nanning 530021,China)
出处
《中华放射肿瘤学杂志》
CSCD
北大核心
2020年第3期225-228,共4页
Chinese Journal of Radiation Oncology
关键词
直肠肿瘤/放化疗法
放化疗法
新辅助
研究进展
Rectal neoplasm/radiochemotherapy
Radiochemotherapy
neoadjuvant
Research progress
