摘要
对毛菊苣(Cichorium glandulosum Boiss.et Huet)地上部分的化学成分进行研究。采用硅胶、Sephadex LH-20、ODS柱色谱、半制备高效液相等多种方法进行分离纯化,通过理化性质及光谱数据对化合物进行结构鉴定。从中分离得到一个新的黄酮苷化合物,鉴定为槲皮素-3-O-[6″-O-(3-乙氧基-1,3-二氧代丙基)]-β-D-吡喃葡糖苷(1)。
Chemical constituents from the air dried parts of Cichorium glandulosum were studied.The chemical constituents of C.glandulosum were separated and purified by means of silica gel,Sephadex-LH 20,ODS column chromatography and semi-preparative high performance liquid chromatography.The structure was elucidated by physicochemical characteristics and spectral data.One new flavonoid glycoside was isolated from C.glandulosum,and identified as quercetin-3-O-[6″-O-(3-ethoxy-1,3-dioxopropyl)]-β-D-glucopyranoside(1).
作者
翁馨
黄敏洁
娄云云
尚靖
张健
殷志琦
WENG Xin;HUANG Minjie;LOU Yunyun;SHANG Jing;ZHANG Jian;YIN Zhiqi(Department of TCMs Pharmaceuticals,School of TCM&State Key Laboratory of Natural Medicines,China Pharmaceutical University,Nanjing 211198;Laboratory of Translational Medicine,Jiangsu Provincial Academy of Traditional Chinese Medicine,Nanjing 210028;Department of Pharmacology of Chinese Materia Medica,School of Traditional Chinese Pharmacy,China Pharmaceutical University,Nanjing,211198,China)
出处
《中国药科大学学报》
CAS
CSCD
北大核心
2020年第1期29-32,共4页
Journal of China Pharmaceutical University
基金
国家“重大新药创制”科技重大专项资助项目(No.2019ZX09301156)。
关键词
毛菊苣
黄酮苷
化学成分
Cichorium glandulosum
flavonoid glycosides
chemical constituents
