强直性肌营养不良的临床特征、肌电图及肌肉病理研究

Clinical characteristics,electromyogram and muscle pathology of myotonic dystrophy

目的研究强直性肌营养不良(DM)的临床特征、肌电图、肌肉病理及诊断学方法。方法总结2008-2011年住院的临床诊断为强直性肌营养不良的5例患者的临床特征、肌电图、肌肉病理学特征进行系统分析。结果5例患者均行肌电图、肌肉病理学检查,5例患者的肌电图程肌源性损害,并发现强直电位,5例患者的肌肉病理活检均符合强直性肌营养不良的病理表现。结论根据患者的临床特点、肌电图检查及肌肉病理可对DM患者进行诊断。

Objective To study the clinical characteristics,electromyogram,muscle pathology and diagnostic methods of myotonic dystrophy(DM).Methods This paper summarized the clinical characteristics,electromyogram and muscle pathology of 5 patients who were clinically diagnosed with myotonic dystrophy in hospital from 2008 to 2011.Results Electromyogram and muscle pathology were performed in all 5 patients.Myogenic lesions and tonic potential were found in the electromyogram of 5 patients.The pathological findings of muscle pathology in 5 patients were consistent with the pathological manifestations of tonic muscle dystrophy.Conclusion DM patients can be diagnosed according to their clinical characteristics,electromyogram examination and muscle pathology.