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从证据的角度客观认识复发性流产中的免疫因素 被引量:14

Understanding of immune factors in recurrent abortion from the evidence perspective
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摘要 复发性流产或复发性胎儿丢失(RPL)的病因复杂多样,与RPL明确相关的免疫因素有且仅有抗磷脂综合征(APS)。APS的诊断应严格满足相应的分类标准,但临床中对部分可能有抗磷脂抗体(aPL)参与流产发病的患者应适当放宽治疗指征。治疗方面应对aPL阳性的患者进行危险分层,根据具体情况给予个体化治疗。目前尚无证据表明单纯低滴度ANA阳性及同种异体免疫与RPL明确相关,国外指南亦不推荐对同种异体免疫进行筛查或治疗。
作者 季兰岚 张卓莉 Ji Lanlan;Zhang Zhuoli(Department of Rheumatology and Clinical Immunology,Peking University First Hospital,Beijing 100034,China)
出处 《中华风湿病学杂志》 CAS CSCD 北大核心 2020年第1期1-6,共6页 Chinese Journal of Rheumatology
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