维生素A、E水平在儿童疱疹性咽峡炎发病中的意义

Significance of Vitamin A and E Levels in the Pathogenesis of Herpetic Isthmus in Children

【目的】探讨血清维生素A、E水平与儿童疱疹性咽峡炎的相关性。【方法】选择2018年10月至2019年9月本院收治的60例疱疹性咽峡炎患儿作为观察组,同期选取健康体检儿童60例作为对照组,比较二组儿童的血清维生素A、E水平。【结果】两组白细胞计数、中性粒细胞百分比、淋巴细胞百分比、CRP水平比较,差异均无统计学意义(P>0.05)。观察组患儿血清维生素A含量正常、边缘型缺乏、临床缺乏三者所占比例显著低于对照组,差异有统计学意义(P<0.05);观察组患儿血清维生素A水平明显低于对照组,差异有统计学意义(P<0.05)。观察组血清维生素E含量正常、缺乏、过量三者所占比例与对照组比较,差异无统计学意义(P>0.05);观察组患儿血清维生素E水平略低于对照组,但差异无显著性意义(P>0.05)。【结论】疱疹性咽峡炎患儿童维生素A临床缺乏、边缘型缺乏均占较高比例,血清维生素A含量均值较正常健康儿童明显降低,可能是疫療性咽峡炎 的易感因素之一。

【objective】To explore the association between serum vitamin A、E levels and herpetic isthmus in children.【Methods】Sixty children with herpes isthmus treated in our hospital from October 2018 to September 2019 were selected as observation group,and 60 children with healthy physical examination were selected as control group in the same period to compare the serum vitamin A、E levels of children in the two groups.【Results】There was no significant difference in leukocyte count,neutrophil percentage,lymphocyte percentage and CRP between the two groups(P>0.05).The proportion of normal serum vitamin a content,marginal type deficiency and clinical deficiency in the observation group was significantly lower than that in the control group(P<0.05);the serum vitamin a level in the observation group was significantly lower than that in the control group(P<0.05).Compared with the control group,there was no significant difference in the proportion of normal,deficient and excessive vitamin E in the serum of the observation group(P>0.05);the level of vitamin E in the serum of the observation group was slightly lower than that of the control group,but there was no significant difference(P>0.05).【Conclusion】Vitamin A clinical deficiency and marginal type deficiency in children with herpetic isthmus are higher,and the average serum vitamin A content is significantly lower than that in normal healthy children,which may be one of the predisposing factors of herpes isthmus.