期刊文献+

对冠心病心肌缺血患者使用替格瑞洛与氯吡格雷治疗的临床疗效分析 被引量:4

Analysis of Clinical Efficacy of Ticagrelor and Clopidogrel in Patients with Coronary Heart Disease and Myocardial Ischemia
下载PDF
导出
摘要 目的探讨冠心病心肌缺血患者使用替格瑞洛与氯吡格雷治疗的临床疗效。方法选取2018年1月至2019年1月在大连市友谊医院就诊的80例冠心病心肌缺血患者,随机分为试验组和对照组,对照组40例采取氯吡格雷治疗,试验组40例采取替替格瑞洛治疗,比较两组患者的心率、收缩压、舒张压水平,以及临床有效率情况。结果试验组舒张压、收缩压及心率水平显著优于对照组(P<0.05);试验组临床有效率高于对照组,差异有统计学意义(P<0.05)。结论对冠心病心肌缺血患使用替格瑞洛治疗,可以有效的提高临床有效率,稳定患者的血压、心率,值得在临床推广。 Objective To investigate the clinical efficacy of glilol and clopidogrel in the treatment of myocardial ischemia in patients with coronary heart disease.Methods From January 2018 to January 2019 in the Dalian friendship hospital hospital,80 cases of 80 patients with coronary heart disease,myocardial ischemia,randomly divided into experimental group and the control group,control group 40 cases treated with clopidogrel,experimental group 40 cases take for Greg treatment,compared two groups of patients with heart rate,systolic pressure,diastolic blood pressure level,as well as clinical effectiveness.Results Diastolic blood pressure,systolic blood pressure and heart rate of the experimental group were significantly better than those of the control group(P<0.05).The clinical effective rate of the experimental group was higher than that of the control group,and the difference was statistically significant(P<0.05).Conclusion The use of glilol and clopidogrel in the treatment of myocardial ischemia patients with coronary heart disease can effectively improve the clinical efficiency and stabilize the patient's blood pressure and heart rate,which is worthy of clinical promotion.
作者 韩玉泽 HAN Yu-ze(Department of Cardiology,Dalian Friendship Hospital,Dalian 116001,China)
出处 《中国医药指南》 2020年第9期21-22,共2页 Guide of China Medicine
关键词 氯吡格雷 替格瑞洛 冠心病 心肌缺血 Clopidogrel Tigrelo Coronary heart disease Myocardial ischemia
  • 相关文献

参考文献6

二级参考文献85

  • 1张伟丽.急性冠脉综合症患者住院期和出院后脑卒中的患病危险因素研究——GRACE研究[J].中国分子心脏病学杂志,2005,5(4):634-634. 被引量:13
  • 2张大真,权正良,李增烈.长期服用小剂量肠溶型阿司匹林对胃十二指肠黏膜损害的病例对照研究[J].胃肠病学,2006,11(7):427-430. 被引量:16
  • 3Yusuf S,Zhao F,Mehta SR,et al. Effects of clopidogrel in addition to asprin in patients with acute coronary syndromes without ST-segmenl elevation[J]. N Engl J Med,2001,345(7):494-502.
  • 4Gorog DA,Sweeny JM,Fuster V. Antiplatelet drug resistance.Part 2:laboratory resistance to antiplatelet drugs-fact or artifact[J]. Nat Rev Cardiol,2009,6(5):365-73.
  • 5Cattaneo M. Resistance to anti-platelet agents[J]. Thromb Res,2011,127(Suppl 3):S61-3.
  • 6Cattaneo M. Aspirin and clopidogrehefficacy,safety,and the issue of drug resistance[J]. Arterioscler Thromb Vasc Biol,2004,24(11): 1980-7.
  • 7Patrono C,Coller B,Dalen JE,et al. Platelet-active drugs:the relationships among dose, effectiveness,and side effects[J]. Chest,1998,114(5 Suppl):470S-88S.
  • 8Wallentin L,Becker RC,Budaj A,et al. Ticagrelor versus clopidogrel in patients with acute coronary syndromes[J]. N Engl J Med,2009,361 (11):1045-57.
  • 9Swallow RA,Agarwala RA,Dawkins KD,et al. Thromboelastograrphy: potential bed side tool to assess the effects of antiplatelet therapy[J]. Platelets,2006,17(6):385-92.
  • 10Hobson AR,Petley GW,Dawkins KD,et al. A novel fifteen minute test for assessment of individual time-dependent clotting responses to aspirin and elopidogrel using modified thrombel astography[J]. Platelets,2007,18(7):497-505.

共引文献92

同被引文献28

引证文献4

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部