裂解酶对食源性病原菌的生物防治研究及应用

Research Progress of Lysins for Biocontrol of Foodborne Pathogens and Its Applications

噬菌体裂解酶能够高效消化细菌细胞壁,对多重耐药病原菌表现出独特的裂解能力,是一种新型抗菌分子,具有重要的应用潜力和研究价值。本文对裂解酶在食品生产中的研究进展进行了概述,重点综述了裂解酶及其嵌合体对食源性病原菌的生物防治研究以及裂解酶作用于革兰氏阴性菌的研究进展。

Bacteriophage lysins have emerged as a new class of antimicrobial agents used for bio-controlling bacterial infection or other unwanted contaminations in various fields,particularly with increasing frequency of drug-resistant pathogens in the worldwide.In the present review,developments regarding the use of lysins for food safety are outlined.Furthermore,lysins for bio-controlling bacterial contamination and novel approaches regarding to lysins towards Gram-negative cells will also be highlighted.