潜在抗冠状病毒药物瑞德西韦研究进展

Research progress of potential anti-coronavirus drug remdesivir

冠状病毒(CoV)是一种正向单链RNA病毒,可以广泛感染人类及其他脊椎动物,部分人畜共患的病毒变异体对人类社会造成了较大影响。瑞德西韦是一种核苷类似物,在细胞及动物实验中表现出了一定的广谱抗病毒作用,具有作为广谱抗CoV药物的潜力。

Coronavirus(CoV) is a forward single-stranded RNA virus that can widely infect humans and other vertebrates. Some zoonotic virus variants have affected human society to some extent. Remdesivir is a nucleoside analog that shows a certain broad-spectrum antiviral effect in cell and animal experiments, and has the potential as a broad-spectrum anti-CoV drug.