无创正压通气结合连续血液净化对心衰合并急性肾衰竭患者预后的影响

Effect of Non-Invasive Positive Pressure Ventilation Combined with Continuous Blood Purification on the Prognosis of Patients with Heart Failure and Acute Renal Failure

目的:探讨无创正压通气结合连续血液净化对心衰合并急性肾衰竭患者预后的影响。方法:按照随机数表法将2016年10月~2018年1月于某院接受治疗的130例心衰合并急性肾衰竭患者分为对照组和观察组各65例,给予对照组患者连续血液净化治疗,观察组在此基础上联合无创正压通气治疗,对比两组患者治疗前后心功能指标、血浆Na^+、K^+、BNP水平及再次住院率。结果:相比对照组,观察组LVEF、CO水平均较高,血浆Na^+、K^+、BNP水平均较低,差异具有统计学意义(P<0.05);相比对照组(29.23%),观察组再次住院率(12.31%)较低,差异具有统计学意义(P<0.05)。结论:对心衰合并急性肾衰竭患者实施无创正压通气结合连续血液净化治疗可有效改善患者心功能指标及血浆Na^+、K^+、BNP水平,降低再次住院率,预后较好。

Objective:To investigate the effect of non-invasive positive pressure ventilation combined with continuous blood purification on the prognosis of patients with heart failure and acute renal failure.Methods:130 patients with heart failure and acute renal failure who treated in the hospital from October 2016 to January 2018 were divided into two groups according to random number table method,with 65 cases in each group.Control group was given continuous blood purification,and observation group was treated with non-invasive positive pressure ventilation based on control group.The cardiac function indexes,plasma Na^+,K^+,BNP,re-hospitalization rate before and after treatment were compared between two groups.Results:Compared with control group,the levels of LVEF and CO in observation group were higher,and the levels of plasma Na^+,K^+ and BNP in observation group were lower(P<0.05);The re-hospitalization rate of observation group(12.31%)was lower than that of control group(29.23%)(P<0.05).Conclusion:Non-invasive positive pressure ventilation combined with continuous blood purification in treatment of patients with heart failure and acute renal failure can improve cardiac function indexes and levels of plasma Na^+,K^+and BNP,decrease the re-hospitalization rate,and have better prognosis.