胰岛素泵与皮下注射胰岛素强化治疗初发2型糖尿病的疗效对比

Comparison of the Effect of Intensive Insulin Pump and Subcutaneous Insulin Injection in the Treatment of First-Onset Type 2 Diabetes

目的:临床研究胰岛素泵与皮下注射胰岛素强化治疗初发2型糖尿病的疗效.方法:选取2016年7月~2018年7月在本院治疗的2型糖尿病患者91例为研究对象进行回顾性分析.将患者归类为胰岛素泵组(观察组):46例患者,采用胰岛素泵方案治疗;间断胰岛素皮下注射组(对照组):45例患者,采取间断胰岛素皮下注射方案治疗.分析组间相关指标变化意义.结果:①经过治疗后发现胰岛素泵组血糖及β细胞功能各项指标对比间断胰岛素皮下注射组具有明显优势,P<0.05.②经过治疗后发现胰岛素泵组血糖达标时间及低血糖情况对比间断胰岛素皮下注射组具有明显优势,P<0.05.结论:新诊断的2型糖尿病患者使用胰岛素泵强化治疗不仅有助于恢复胰岛β细胞功能,降低患者血糖,而且与间歇性胰岛素皮下注射相比,还可降低平均血糖顺应时间和低血糖.

Objective:To compare the efficacy of insulin pump and subcutaneous insulin injection in the treatment of first-onset type 2 diabetes.Methods:In this study,91 patients with type 2 diabetes treated in our hospital from July 2016 to July 2018 were retrospectively analyzed.The patients were classified into the insulin pump group(study group):46 patients were treated with the insulin pump scheme;the intermittent insulin subcutaneous injection group(control group):45 patients were treated with the intermittent insulin subcutaneous injection scheme.Analyze the significance of changes in related indicators between groups.Results:①After treatment,it was found that the indexes of blood glucose andβ-cell function of the insulin pump group had obvious advantages compared with the intermittent insulin subcutaneous injection group P<0.05.②After treatment,it was found that the insulin pump group’s blood glucose compliance time and hypoglycemia were significantly superior to the intermittent insulin subcutaneous injection group P<0.05.Conclusion:Intensive treatment with insulin pump in newly diagnosed patients with type 2 diabetes not only helps to restore isletβ-cell function and reduce patients’blood glucose,but also reduces average blood glucose compliance time and hypoglycemia compared with intermittent subcutaneous insulin injection.