老年慢病共存患者多重用药负担研究进展

Recent Advances in Burden of Multiple Medications in Elderly Patients with Multimorbidity

老年慢病共存患者多重用药负担在影响其用药信念、用药行为和健康转归方面起着核心作用,关注老年慢病共存患者多重用药负担或可为解决其用药问题提供新角度,但鲜有研究对国内外老年慢病共存患者多重用药负担研究进展进行报道。本研究旨在明确患者用药负担的定义,并对国内外开展的有关老年慢病共存患者用药负担的研究进行梳理,总结其用药负担研究现状,并进一步分析其影响因素,即一般人口学资料、疾病药物治疗方案复杂性、药物本身特征、患者用药态度和药物素养以及家庭社会因素等,以期为降低我国老年慢病共存患者多重用药负担提供科学参考。

The burden of multiple medications is a foremost factor associated with medication beliefs,medication behavior and health outcomes in elderly patients with multimorbidity.So paying attention to the multiple medication burden may provide a new perspective for solving medication problems in this group.However,its research development is rarely reviewed.In this study,we gave a clear definition of medication burden,reviewed various studies about medication burden in elderly patients with multimorbidity,and summarized the recent research status,and analyzed general demographic data,complexity of medication regimens,medicine characteristics,patients’ medication attitude and medication literacy,and family and social factors associated with medication burden,with a view to providing a scientific reference for reducing the burden of multiple medications in Chinese elderly patients with multimorbidity.