HPV感染患者焦虑现状及相关影响因素分析

Anxiety Status and Related Influencing Factors in Patients with HPV Infection

目的:研究人乳头瘤病毒(HPV)感染患者焦虑发生状况及相关影响因素。方法:选取2019年5月7月在首都医科大学附属北京妇产医院妇科肿瘤门诊就诊的HPV阳性患者300例作为研究对象,通过填写一般问卷及焦虑自评量表(SAS)收集资料,分析HPV感染患者焦虑发生现状及相关影响因素。结果:300例患者中,焦虑发生率为37.00%(111/300),其中轻度焦虑占70.27%(78/111),中度焦虑占20.72%(23/111),重度焦虑占9.01%(10/111),焦虑评分为(45.23±12.05)分。不同年龄、文化程度、职业、居住地、HPV感染时间及家庭年收入的HPV感染患者焦虑发生率和焦虑评分差异有统计学意义(均P<0.05)。Logistic回归分析显示,短期无固定工作/无业(OR=3.037,95%CI:1.524~6.049,P=0.002)、居住于农村(OR=2.198,95%CI:1.140~4.237,P=0.019)、HPV持续感染时间≤3个月(OR=5.972,95%CI:2.764~12.905,P<0.001)或>1年(OR=5.571,95%CI:2.692~11.529,P<0.001)、家庭年收入≤8万(OR=1.922,95%CI:1.038~3.557,P=0.038)是引起HPV感染患者焦虑的独立影响因素。结论:HPV感染患者的焦虑发生率及焦虑评分较正常健康人群均升高。对于短期无固定工作/无业、居住于农村、HPV持续感染时间≤3个月或>1年及低收入的患者在治疗原发疾病的同时,应注重其心理状况,及早发现异常并积极干预。

Objective:To study the incidence of anxiety and related factors in patients with human papillomavirus(HPV)infection.Methods:From May to July 2019,300 HPV-positive patients who were admitted to the gynecological oncology clinic of the Beijing Obstetrics and Gynecology Hospital affiliated to Capital Medical University were selected as subjects.By filling in the general questionnaire and self-rating anxiety scale(SAS),the data were collected to analyze the current situation and related influencing factors of anxiety in patients with HPV infection.Results:Among the 300 patients,the incidence of anxiety was 37.00%(111/300),of which mild anxiety accounted for 70.27%(78/111),moderate anxiety accounted for 20.72%(23/111),and severe anxiety accounted for 9.01%(10/111),and the anxiety score was 45.23±12.05.There was significant difference in anxiety rate and score among patients with HPV infection in different age,education level,occupation,residence,time of HPV infection and family income(P<0.05).Logistic regression analysis showed that short-term non fixed work/non employment(OR=3.037,95%CI:1.524-6.049,P=0.002),living in rural(OR=2.198,95%CI:1.140-4.237,P=0.019),duration of persistent infection of HPV≤3 months(OR=5.972,95%CI:2.764-12.905,P<0.001),or>1 year(OR=5.571,95%CI:2.692-11.529,P<0.001),and annual household income≤0.8 million(OR=1.922,95%CI:1.038-3.557,P=0.038)were independent factors of anxiety in patients with HPV infection.Conclusions:The incidence and score of anxiety in patients with HPV infection were higher than those in normal healthy people.For short-term non fixed work/non employment,living in rural areas,duration of HPV infection(≤3 months,>1 year)and low-income patients,attention should be paid to their psychological status while treating the primary diseases,so as to detect abnormalities as early as possible and actively intervene.