多糖基抗菌膜制备的研究进展

Progress in Preparation of Polysaccharide-based Antimicrobial Membrane

目的综述了近年来多糖基抗菌膜制备的研究进展,为多糖基抗菌薄膜材料进一步的制备与发展提供科学的研究基础。方法通过对已有研究的现状和研究结果分析和总结,介绍了多糖基抗菌膜基材的种类、制备方法的研究进展。结果共混、浇铸、涂覆及静电纺丝等物理手段,溶解-插入的表面改性方式及化学交联法,为多糖基抗菌膜制备的主要方式。结论物理手段为常用制膜方式,故对天然抗菌剂的开发需求迫切。单一多糖基抗菌膜综合性能不足,应用容易受限,复合膜综合性能良好,但阻隔性能及缓释机理有待进一步研究。

The paper aims to overview the research progress in preparation of polysaccharide-based antibacterial membrane in recent years so as to provide a scientific basis for further preparation and development of polysaccharide-based antibacterial membrane.Based on analysis and summary of existing research status and results,the types and preparation methods of polysaccharide-based antibacterial membrane substrate were introduced.Physical means such as blending,casting,coating and electrospinning,dissolution-insertion,and chemical cross-linking were the main methods for preparation of polysaccharide-based antibacterial membranes.Physical means are commonly used to make membrane,thus it is urgent to develop natural antibacterial agent.The comprehensive performance of single polysaccharide-based antibacterial membrane is insufficient,its application is easily limited,and the comprehensive performance of composite membrane is good,but the barrier performance and slow release mechanism need to be further studied.