持续性心房颤动与二度房室传导阻滞的相关性研究

Association Between Persistent Atrial Fibrillation and Second-degree Atrioventricular Block

目的探讨持续性心房颤动与二度房室传导阻滞之间的相关性。方法本研究为1∶1配对的病例对照研究。纳入2016年5月—2019年5月在本院住院就诊持续性心房颤动患者170例,同时配对性别相同、年龄相差3岁以内的同期住院患者170例。分析心房颤动患者中二度房室传导阻滞的发生率,使用负二项回归探讨心房颤动与二度房室传导阻滞之间的相关性。结果心房颤动组中二度房室传导阻滞的比例为13/170(7.6%),远远高出非心房颤动组(1/169),且存在统计学差异。负二项回归统计显示:两组间无二度房室传导阻滞/二度房室传导阻滞的相对统计学危险度为0.901(P<0.001)。结论心房颤动患者中二度房室传导阻滞并不少见,二度房室传导阻滞与心房颤动密切相关。

Objective To investigate the relationship between persistent atrial fibrillation and second-degree atrioventricular block.Methods This study was a one to one matched case-control study.The patients with persistent atrial fibrillation in our hospital from May 2016 to May 2019 were included.170 inpatients with the same sex and age difference of less than 3 years were matched at the same time.The incidence of second-degree atrioventricular block in patients with atrial fibrillation was analyzed,and the binomial distribution was used to explore the association between atrial fibrillation and second-degree atrioventricular block.Results The proportion of second-degree atrioventricular block in atrial fibrillation group was 10%,which was much higher than that in non-atrial fibrillation group,and there was statistical difference.Negative binomial regression analysis showed that the statistical risk of no second-degree atrioventricular block in atrial fibrillation group was 0.901(P<0.001).Conclusion Second-degree atrioventricular block is not uncommon in patients with atrial fibrillation.Second-degree atrioventricular block is closely related to atrial fibrillation and may be a risk factor for atrial fibrillation.