胃肠道间质瘤MSCT表现与危险度相关性研究

Correlation Study between Pathological Grading and MSCT Findings on Gastrointestinal Stromal Tumors

目的研究胃肠道间质瘤MSCT表现与危险度的相关性.方法回顾性分析20例经病理证实的胃肠道间质瘤MSCT表现,并与病理危险度对照.结果发生于胃16例,小肠4例;大小≥5 cm有13例,<5 cm有7例;边缘规则12例,不规则8例;实性12例,囊实性8例;伴溃疡6例;伴钙化5例.增强扫描静脉期较动脉期CT值升高的有18例,减低的有2例;延迟期较静脉期CT值升高的有9例,减低的有11例.术后病理危险度评估极低危险性5例,低度危险性3例,中度危险性5例,高度危险性7例.结论胃肠道间质瘤MSCT表现中肿瘤的大小、边缘与危险度具有明显相关性,肿瘤的发生部位、有无囊变、有无溃疡、有无钙化及增强CT值改变与危险度无明显相关性,此可为术前诊断、治疗方案的选择提供更加丰富、合理的理论依据.

Objective To investigate the correlation between MSCT findings and pathological risk grading on gastrointestinal stromal tumors(GIST).Methods A total of 20 gastrointestinal stromal tumor cases with pathological confirmation were enrolled into current study.MSCT findings of every case were recorded,analyzed and compared with pathological grading on risk assessment.Results Among the 20 cases of GIST,16 cases were originated from stomach,while 4 cases derived from small intestine;13 cases5 diameter were≥5 cm,while 7 were<5 cm;12 cases presented regular margin while 8 cases manifested irregular margin;12 cases were substantive lesion,while 8 were solid-cystic;ulcer and calcification were found in 6 and 5 cases,respectively.After enhancement in MSCT,18 cases showed higher CT values during venous phase than arterial phase,while 2 cases showed opposite direction;9 cases showed higher CT values during delay phase than venous phase,while 11 cases showed opposite direction.Post-surgery pathological risk grading evaluation confirmed that 5 cases were classified into very low risk group,3 cases were low risk,5 cases were intermediate risk and 7 cases were high risk.Conclusion Statistically significant positive correlation existed between tumor size,margin measured by MSCT and pathological risk grading,whereas no statistically significant correlation existed between tumor location,cystic change,ulcer,calcification,CT values alteration and pathological risk grading.Above-mentioned significant correlation could provide more substantial and reasonable evidence for pre-surgery diagnosis and therapeutic options.