冰冻切片在卵巢肿瘤手术中的病理诊断研究

Pathological diagnosis study of frozen sections in ovarian tumor surgery

目的探讨冰冻切片在卵巢肿瘤手术中的病理诊断效果。方法入选本研究60例研究对象均为我院收治的卵巢肿瘤患者,病例选择时间为2016年3月~2019年3月,手术过程中对其实施冰冻切片诊断,完成手术后实施石蜡切片诊断,比较其诊断结果。结果(1)冰冻切片检查时间少于石蜡切片检查时间,差异有统计学意义(P<0.05);(2)60例患者手术中进行冰冻切片诊断正确率为93.33%(56/60),良性肿瘤诊断正确率为100.00%,恶性肿瘤诊断正确率为83.33%,误诊率为16.67%,交界性肿瘤诊断正确率为78.57%,误诊率为22.43%;(3)60例肿瘤患者组织来源分别为18例生殖细胞肿瘤,24例上皮源性肿瘤,10例性索间质肿瘤以及8例其他肿瘤,生殖细胞肿瘤确诊率为88.88%,延迟诊断率为5.56%,误诊率为5.56%,上皮源性肿瘤确诊率为91.66%,延迟诊断率为4.17%,误诊率为4.17%,性索间质肿瘤确诊率为90.00%,延迟诊断率为10.00%,其他肿瘤确诊率为100.00%。结论手术前以及手术过程中病理医生和临床医生需要进行交流,并依据检查结果、手术情况以及患者病史等方面进行探究,以此对其进行诊断,为患者后续治疗提供依据,而冰冻切片可将诊断时间减少,在短时间内对肿瘤性质进行判断,应用效果良好。

Objective To investigate the pathological diagnosis of frozen sections in ovarian tumor surgery.Methods 60 patients included in this study were all ovarian tumor patients treated in our hospital.The case selection period was from March 2016 to March 2019.Frozen section diagnosis was performed during the operation,and paraffin section diagnosis was performed after the operation.The diagnosis results were compared.Results(1)The frozen section examination time was shorter than the paraffin section examination time,and the data difference between the groups was statistically significant(P<0.05).(2)Of the 60 patients,the correct rate of frozen section diagnosis the operation was 93.33%(56/60),the correct rate of benign tumor diagnosis was 100.00%,the correct rate of malignant tumor diagnosis was 83.33%,the misdiagnosis rate was 16.67%,the correct rate of borderline tumors diagnosis was 78.57%,and the misdiagnosis rate was 22.43%.(3)Of the 60 patients with tumors,18 were derived from germ cell tumors,24 were epithelial-derived tumors,10 were sex cord-stromal tumors,and 8 were other tumors.Among germ cell tumors,the diagnosis rate was 88.88%,the delayed diagnosis rate was 5.56%,and the misdiagnosis rate was 5.56%.Among epithelial-derived tumors,the diagnosis rate was 91.66%,the delayed diagnosis rate was 4.17%,and the misdiagnosis rate was 4.17%.Among sex cord-stromal tumors,the diagnosis rate was 90.00%,the delayed diagnosis rate was 10.00%,and the diagnosis rate of other tumors was 100.00%.Conclusion Pathologists and clinicians need to communicate before and during surgery,and to investigate based on the results of the examination,the situation of the operation,and the patient’s medical history in order to diagnose the patient and provide a basis for subsequent treatment of the patient.Frozen sections can reduce the diagnosis time,determine the nature of tumors in a short time,and have a good application effect.