盐酸哌甲酯控释片联合静灵口服液治疗小儿多动症的效果研究

Study on the Effect of Methylphenidate Hydrochloride Controlled-release Tablets Combined with Jingling Oral Liquid in Treatment of ADHD in Children

目的:探讨小儿多动症应用盐酸哌甲酯控释片联合静灵口服液治疗的临床效果。方法:选取2016年1月-2019年8月笔者所在医院儿科收治的82例小儿多动症患者,对照组应用盐酸哌甲酯控释片治疗,研究组应用盐酸哌甲酯控释片及静灵口服液治疗,比较两组临床治疗效果。结果:研究组治疗总有效率(97.56%)高于对照组(78.05%),差异有统计学意义(P<0.05)。研究组动作活动多、易冲动、注意力不集中及情绪波动大评分均低于对照组,差异均有统计学意义(P<0.05)。研究组不良反应发生率(4.88%)低于对照组(26.84%),差异有统计学意义(P<0.05)。结论:对小儿多动症患儿选择盐酸哌甲酯控释片联合静灵口服液治疗,效果明显,符合临床需求,可保证治疗的安全性,值得在临床中推广应用。

Objective:To explore the clinical effect of Methylphenidate Hydrochloride Controlled-release Tablets combined with Jingling Oral Liquid in treatment of ADHD in children.Method:From January 2016 to August 2019,82 children with ADHD admitted to our hospital were selected.The control group was treated with Methylphenidate Hydrochloride Controlled-release Tablets.The study group was treated with Methylphenidate Hydrochloride Controlled-release Tablets and Jingling Oral Liquid.The clinical therapeutic effects of the two groups were compared.Result:After treatment,the total effective rate of the study group(97.56%)was higher than that of the control group(78.05%),the difference was statistically significant(P<0.05).The scores of activity,impulsiveness,inattention and mood fluctuation in the study group were lower than those in the control group,the differences were statistically significant(P<0.05).The incidence of adverse reactions in the study group(4.88%)was lower than that in the control group(26.84%),the difference was statistically significant(P<0.05).Conclusion:The combination of Methylphenidate Hydrochloride Controlled-release Tablets and Jingling Oral Liquid is effective in the treatment of children with ADHD,which can meet the clinical needs,ensure the safety of the treatment,and is worthy of clinical application.