氯胺酮为麻醉剂的MECT效果

MECT Effect of Ketamine as Anesthetics

目的:探讨氯胺酮为麻醉剂的MECT效果.方法:将2017年4月-2019年4月于笔者所在医院进行MECT治疗的102例患者作为研究对象,按照随机数字法分为两组,对照组52例,观察组50例.对照组行丙泊酚麻醉,观察组行氯胺酮麻醉.对比两组临床指标及阳性与阴性症状量表(PANSS)评分,并记录治疗过程中不良反应情况.结果:治疗后,观察组抽搐能量指数为(15102±3305),低于对照组的(20001±3518),差异有统计学意义(P<0.05);观察组治疗后阳性及阴性因子评分分别为(12.25±3.12)、(16.74±4.25)分,均低于对照组的(18.71±3.87)、(24.89±7.79)分,差异均有统计学意义(P<0.05);观察组不良反应发生率为10.00%,低于对照组的59.62%,差异有统计学意义(P<0.05).结论:在进行MECT治疗过程中,氯胺酮与丙泊酚具有相近的麻醉效果,但前者能显著改善PANSS评分,且不良反应发生率低,安全性更高,值得在临床中推广使用.

Objective:To study the MECT effect of Ketamine as anesthetics.Method:A total of 102 patients who were treated with MECT in our hospital from April 2017 to April 2019 were selected as the study objects and divided into two groups according to the random number method,52 cases in the control group and 50 cases in the observation group.The control group was given Propofol anesthesia and the observation group was given Ketamine anesthesia.Clinical indicators and positive and negative symptom scale(PANSS)scores of the two groups were compared,and the adverse reactions were recorded.Result:After treatment,the twitch energy index of the observation group was(15102±3305),which was lower than(20001±3518)of the control group,and the difference was statistically significant(P<0.05).After treatment,the scores of positive and negative factors of the observation group were(12.25±3.12),(16.74±4.25)points,which were lower than(18.71±3.87),(24.89±7.79)points of the control group,and the differences were statistically significant(P<0.05).The incidence of adverse reactions of the observation group was 10.00%,which was lower than 59.62%of the control group,and the difference was statistically significant(P<0.05).Conclusion:Ketamine and Propofol have similar anesthetic effect in MECT treatment,but the former can improve the PANSS score greatly,and the incidence of adverse reactions is lower and the safety is higher,which is worthy of clinical application.