糖尿病视网膜病的发病机制及药物干预研究进展

Research progress of pathogenesis and drug intervention of diabetic retinopathy

随着糖尿病发病率的升高,糖尿病的各种并发症也呈上升趋势。糖尿病视网膜病变(DR)是糖尿病晚期的严重并发症之一,其致病过程受多因素、多环节、多基因影响,但具体机制尚不明确,缺少疗效显著的药物。DR作为临床上常见的致盲性眼病,其治疗也一直是研究热点。该文就近年来DR的危险因素、发病机制及其治疗的研究进展做一综述,旨在为临床防治DR提供参考。

With the increasing morbidity of diabetes,diabetic complications are also on the rise.Diabetic retinopathy is one of the severe complications in the late-stage diabetes.As a common blindness disease in clinic,diabetic retinopathy treatment has been a research focus.The pathogenesis of diabetic retinopathy is affected by multiple factors,multiple links and multiple genes,but the specific mechanism is not clear and it lacks effective drugs.This paper reviews the pathogenesis and treatment of risk factors of diabetic retinopathy and wish to provide reference for clinical prevention and treatment of DR.