加速康复外科在结直肠癌中的应用

Application of enhanced recovery after surgery in colorectal cancer

目的:探究加速康复外科在结直肠癌中的应用。方法:选择2018年3月至2019年4月在泰州市人民医院就诊的结直肠癌患者150例,根据随机数表法分为对照组及观察组,对照组给予常规围术期护理,观察组给予加速康复外科护理,对照组及观察组均随访至术后30 d。检测对照组及观察组的营养状况、炎症因子水平、免疫水平,统计术后恢复情况及术后严重并发症发生情况。结果:观察组术后7 d的血红蛋白、前白蛋白、白蛋白及转铁蛋白水平高于对照组(P<0.05);观察组术后7d的白细胞介素-6、C反应蛋白水平低于对照组(P<0.05);观察组术后7 d的CD3+,CD4+及CD4+/CD8+水平高于对照组(P<0.05);观察组术后恢复时间短于对照组(P<0.05);观察组与对照组严重并发症发生情况无差异(P>0.05)。结论:在结直肠癌护理中应用加速康复外科可缩短术后恢复时间且不增加术后并发症发生率。

Objective:To explore application of enhanced recovery after surgery(ERAS)in colorectal cancer.Methods:A total of 150 patients with colorectal cancer who were treated in the hospital from March 2018 to April 2019 were enrolled.They were divided into the control group and the observation group according to random number table method.The control group was given routine perioperative nursing,while observation group was given ERAS nursing.Both groups were followed up till 30 days after surgery.The nutrition status,inflammatory factor levels and immune levels of both groups were detected.The postoperative recovery and incidence of severe complications were statistically analyzed.Results:At 7 days after operation,levels of hemoglobin,prealbumin,albumin and transferrin in the observation group were higher than those in the control group(P<0.05).At 7 days after operation,levels of interleukin-6 and C-reactive protein in observation group were lower than those in the control group.At 7 days after operation,levels of CD3+,CD4+and CD4+/CD8+in the observation group were higher than those in the control group(P<0.05).The postoperative recovery time in the observation group was shorter than that in the control group(P<0.05).There was no significant difference in conditions of severe complications between the two groups(P>0.05).Conclusion:The application of ERAS in nursing for colorectal cancer can shorten postoperative recovery time,without increasing incidence of postoperative complications.