胺碘酮治疗冠心病快速心律失常的临床疗效及对患者血流动力学的影响

Clinical efficacy of amiodarone in the treatment of tachyarrhythmia of coronary heart disease and its influence on hemodynamics

目的:对冠心病快速心律失常急诊患者应用胺碘酮治疗,并观察疗效。方法:选取急诊治疗的98例冠心病快速心律失常患者,将患者分为两组。对照组49例,使用利多卡因等药物进行常规治疗;观察组49例,在对照组基础上使用胺碘酮治疗。结果:观察组治疗有效率为87.76%,对照组为67.35%,差异有统计学意义(P<0.05);治疗后,观察组患者的高切全血黏度、低切全血黏度、纤维蛋白原等血液流变学指标均明显优于对照组,差异有统计学意义(P<0.05)。结论:对冠心病快速心律失常急诊患者采取胺碘酮治疗能够提升治疗效果,改善血液流变学指标。

Objective To observe the therapeutic effect of amiodarone in emergency patients with tachyarrhythmia of coronary heart disease.Method 98 patients with tachyarrhythmia of coronary heart disease who were treated were selected and divided into two groups.49 cases in the control group were treated with lidocaine and other drugs,while 49 cases in the observation group were treated with amiodarone.Results The effective rate of the observation group was 87.76%,and that of the control group was 67.35%.The difference was statistically significant(P<0.05).After treatment,the hemorheological indexes such as high shear whole blood viscosity,low shear whole blood viscosity and fibrinogen in the observation group were significantly better than those in the control group(P<0.05).Conclusion Amiodarone treatment can improve the therapeutic effect and hemorheological indexes of emergency patients with rapid arrhythmia of coronary heart disease.