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盐酸溴己新联合阿奇霉素治疗小儿支原体肺炎的疗效及对患儿血清炎性因子水平的影响 被引量:9

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摘要 目的:探讨采用盐酸溴己新+阿奇霉素的联合治疗方案治疗小儿支原体肺炎的效果。方法:将78例支原体肺炎患儿随机分成观察组(n=39)与对照组(n=39),在患儿入院后均予以抗感染、止咳等常规治疗,常规治疗基础上给予对照组患儿静脉滴注阿奇霉素,给予观察组患儿静脉滴注盐酸溴己新与阿奇霉素,评价两组患儿症状缓解及治疗前后血清T细胞亚群变化。结果:在体温恢复正常、咳嗽消失及肺部啰音等症状缓解时间上,观察组均较对照组短,差异有统计学意义(P<0.05);在治疗后,患儿CD 4、CD 4/CD 8指标水平均较治疗前升高,CD 8指标较治疗前降低,但是观察组指标升高/降低幅度要较对照组显著,差异有统计学意义(P<0.05);临床治疗中观察组与对照组不良反应发生率上差异无统计学意义(P>0.05)。结论:采取盐酸溴已新联合阿奇霉素的治疗方案治疗小儿支原体肺炎,可取得显著效果,加快患儿症状缓解及改善血清炎性因子水平,值得推广。
作者 许洪龙
出处 《吉林医学》 CAS 2020年第4期885-886,共2页 Jilin Medical Journal
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