针刺治疗脑卒中后认知障碍的机制研究进展

Research Progress on the Mechanism of Acupuncture in Treating Cognitive Impairment after Stroke

针刺治疗为治疗脑卒中后认知功能障碍的干预方法之一,临床应用及相关机理研究均证实,针刺治疗具有肯定疗效。通过阅读相关文献,发现多以临床应用进展及临床观察类研究居多,针对针刺治疗该病的相关机制概述居少,该文概述其主要作用机制有调节中枢胆碱能、调节单胺类神经递质、改善海马相关结构的中枢机制和调节自由基、炎症因子、改善血流动力学及调节胰岛素样生长因子IGF-1等方面的外周机制,以期为针刺治疗脑卒中认知障碍临床应用提供实验依据。

Acupuncture is one of the intervention methods for treating cognitive dysfunction after stroke.Clinical application and related mechanism studies have confirmed that acupuncture has a certain effect.Through reading the relevant literature,it is found that most of the clinical application progress and clinical observation studies are mostly,and the relevant mechanisms for acupuncture treatment of the disease are summarized.Transmitters,central mechanisms that improve hippocampal related structures and peripheral mechanisms that regulate free radicals,inflammatory factors,improve hemodynamics,and regulate insulin-like growth factor IGF-1,etc.,with a view to the clinical application of acupuncture in the treatment of stroke cognitive impairment Provide experimental basis.