新型冠状病毒肺炎疫情防控期间遗传性共济失调患者管理策略专家共识

Expert consensus on the management strategy of patients with hereditary ataxia during prevention and control of novel coronavirus pneumonia epidemic

2019年12月以来,在湖北省武汉市陆续发现了一系列传染性极强的不明原因肺炎病例,后经证实为感染"严重急性呼吸道综合症冠状病毒2型(severe acute respiratory syndrome coronavirus 2,SARS-CoV-2)"所致的"2019冠状病毒病(corona virus disease 2019,COVID-19)"。SARS-CoV-2病毒能够侵犯人体肺部等多个系统,中枢神经系统受累者会表现出一系列的神经症状,容易误诊漏诊,从而增加了COVID-19扩散的风险。遗传性共济失调(hereditary ataxia)是一大类具有高度的临床和遗传异质性、病死率和病残率较高的神经系统退行性疾病。鉴于疫情的严重性,政府采取的一系列防控措施,使得许多患者去医院的随访和诊疗受到了限制,对于患者的心身健康产生了较大的影响。为使患者在疫情防控期间得到规范的管理,中国医师协会神经内科医师分会神经遗传专委会特别制定了本共识,旨在帮助患者共克时艰,平安度过防疫期。

Since December 2019,a series of highly infectious cases of unexplained pneumonia have been discovered in Wuhan,Hubei Province,which have been confirmed as"2019 corona virus disease(COVID-19)"caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).SARS-CoV-2 virus can invade many human systems including the lungs.Patients with central nervous system involvement may show a series of neurological symptoms,which is easy to be misdiagnosed and neglected,thereby increasing the risk of SARS-CoV-2 transmission.Hereditary ataxia is a large group of neurodegenerative diseases with great clinical and genetic heterogeneity and high mortality and disability.In view of the seriousness of the COVID-19 epidemic,a series of prevention and control measures adopted by the government have restricted the follow-up,diagnosis and treatment of patients by the hospitals,which has a great impact on their mental and physical health.In order to standardize the management of patients during the prevention and control of COVID-19 epidemic,the Specialized Committee of Neurogenetics of the Neurophysician Branch of Chinese Medical Doctor Association has formulated this consensus,with an aim to help patients overcome the difficulties and pass the epidemic prevention period safely.