神经导航辅助下显微手术治疗幕上脑胶质瘤

Neuronavigation assisted microsurgery for supratentorial glioma

目的评估神经导航辅助下显微手术治疗幕上脑胶质瘤的临床价值。方法回顾性分析南京市第一医院2013年2月至2019年3月收治的43例幕上脑胶质瘤患者临床资料。其中导航组22例,在神经导航辅助下行显微手术治疗;对照组21例,行传统的显微手术治疗。比较两组患者的肿瘤全切除率、手术时间、住院时间、手术后并发症发生率和术后3个月的Karnofsky功能状态(KPS)评分。结果导航组患者的肿瘤全切除率和术后3个月的KPS评分高于对照组[分别为77.3%vs.47.6%,(90.45±11.33)分vs.(80.95±14.46)分],差异均有统计学意义(P<0.05),而两组的手术时间、住院时间和术后并发症发生率差异无统计学意义(P>0.05)。结论神经导航辅助下显微手术治疗幕上脑胶质瘤能准确定位肿瘤,提高患者肿瘤全切除率,改善患者术后3个月的KPS评分,且不增加术后的并发症。

Objective To evaluate the clinical value of neuronavigation-assisted microsurgery for supratentorial glioma.Methods Forty-three cases of supratentorial glioma in our hospital from February 2013 to March 2019 were analyzed retrospectively.In the navigation group,22 cases were treated with microsurgery assisted by neuronavigation,while in the control group,21 cases were treated with traditional microsurgery.Total tumor resection rate,duration of surgery,length of hospital stay,incidence of postoperative complications and Karnofsky performance status scale(KPS)3 months after surgery were compared between the two groups.Results The total tumor resection rate(77.3%vs.47.6%)and the score of KPS 3(90.45±11.33)vs.(80.95±14.46)months after surgery in the navigation group were higher than those in the control group significantly(P<0.05),while the differences in duration of surgery,length of hospital stay,and incidence of postoperative complications between the two groups were not statistically significant(P>0.05).Conclusions Neuronavigation-assisted microsurgery for supratentorial glioma can accurately locate the tumor,improve the total tumor resection rate and KPS 3 the score of months after surgery,without increasing postoperative complications.