纳米炭混悬液在腔镜甲状腺癌手术中的应用

Application of nano-carbon suspension in the endoscopic surgery for thyroid cancer

目的研究纳米炭混悬液在腔镜甲状腺癌手术中的应用效果。方法 82例采取经乳晕入路腔镜甲状腺癌手术患者,随机分为观察组(40例)和对照组(42例)。观察组在手术中应用纳米炭混悬液,对照组在手术中未应用纳米碳混悬液。比较两组中央区淋巴结清扫数目、一过性低钙血症、暂时性甲状旁腺功能低下、永久性甲状旁腺功能低下、甲状旁腺误切发生情况。结果观察组术后一过性低钙血症、暂时性甲状旁腺功能低下发生率与对照组比较差异无统计学意义(P>0.05);两组均未发生永久性甲状旁腺功能低下;观察组甲状旁腺误切发生率2.5%(1/40)明显低于对照组的19.1%(8/42),中央区淋巴结清扫数目(6.0±2.0)枚明显多于对照组的(3.2±1.7)枚,差异均有统计学意义(P<0.05)。结论临床上在腔镜甲状腺癌手术中应用纳米炭混悬液对减少甲状旁腺误切、增加淋巴结清扫数目具有重要的意义,值得临床推广。

Objective To study the application effect of nano-carbon suspension on parathyroid gland in the endoscopic surgery for thyroid cancer. Methods A total of 82 patients undergoing laparoscopic approach for endoscopic thyroid cancer surgery were randomly divided into observation group(40 cases) and control group(42 cases). The observation group was treated with nano-carbon suspension during operation, while the control group was not treated with nano-carbon suspension during operation. The number of lymph node dissections in the central area, occurrence of transient hypocalcemia, temporary hypoparathyroidism, permanent hypoparathyroidism, and parathyroidectomy by mistake were compared between the two groups. Results There was no significant difference in the incidence of transient hypocalcemia and temporary hypoparathyroidism between the observation group and the control group(P>0.05). There was no permanent hypoparathyroidism in both groups. The incidence of parathyroidectomy by mistake 2.5%(1/40) in the observation group was obviously lower than 19.1%(8/42) in the control group, and number of lymph node dissections in the central area(6.0±2.0) pieces was obviously more than(3.2±1.7) pieces in the control group. Their difference was statistically significant(P<0.05). Conclusion The application of nano-carbon suspension in endoscopic surgery for thyroid cancer is of great significance to reduce the number of parathyroidectomy by mistake and increase the number of lymph node dissections. It is worthy of clinical promotion.