多索茶碱联合噻托溴铵粉治疗慢性阻塞性肺疾病的效果

Effect of Combination of Doxofylline and Tiotropium Bromide Powder on Pulmonary Function in Patients With Chronic Obstructive Pulmonary Disease

目的对多索茶碱与噻托溴铵粉联合治疗慢性阻塞性肺疾病患者的效果进行详细的探讨。方法选取102例2017年2月—2019年6月在本院治疗的慢性阻塞性肺疾病患者,随机分为对照组和观察组,各51例,给对照组患者给予多索茶碱治疗,给观察组患者给予多索茶碱联合噻托溴铵粉治疗,观察并比较两组患者的治疗效果以及肺功能的改善情况。结果观察组治疗效果(92.16%)优于对照组(62.75%),差异具有统计学意义(P<0.05);治疗前,观察组患者各项肺功能指标与对照组差异无统计学意义(P>0.05),经过不同的治疗后,观察组与对照组各项肺功能指标与治疗前相比较均有所改善,差异有统计学意义(P<0.05);观察组肺功能各项指标均优于对照组,差异具有统计学意义(P<0.05)。结论临床上治疗慢性阻塞性肺疾病患者时,将多索茶碱与噻托溴铵粉治联合起来使用,对改善患者肺功能及促进患者病情的恢复起到了积极的促进作用,效果显著。

Objective To investigate the effect of combination of doxofylline and tiotropium bromide on lung function in patients with chronic obstructive pulmonary disease.Methods A total of 102 patients with chronic obstructive pulmonary disease who were treated in our hospital from February 2017 to June 2019 were randomly divided into the control group and the observation group,51 cases each.The patients in the control group were treated with doxofylline for observation.Patients in the group were treated with doxofylline combined with tiotropium bromide powder.The therapeutic effects and improvement of lung function were observed and compared between the two groups.Results The therapeutic effect of the observation group(92.16%)was better than that of the control group(62.75%),the difference was significant(P<0.05).Before treatment,there was no significant difference between the observation group and the control group(P>0.05).After different treatment,all lung function indexes in the observation group and the control group were improved compared with those before treatment,the difference was statistically significant(P<0.05)The indexes of lung function in the observation group were better than the control group,the difference was significant(P<0.05).Learning meaning.Conclusion The clinical use of doxofylline combined with tiotropium bromide powder in the treatment of patients with chronic obstructive pulmonary disease can effectively improve the lung function of patients and promote the recovery of patients'condition.The effect is significant and has a high promotion value.