摘要
目的观察丹红注射液治疗急性脑梗死的临床疗效。方法采用回顾性分析方法,将符合诊断标准的60例脑梗死患者随机分为丹红注射液治疗组(丹红治疗组)30例和曲克芦丁注射液治疗组(芦丁对照组)30例。2组均予以常规治疗,丹红治疗组在常规治疗基础上加用丹红注射液治疗,芦丁对照组在常规治疗基础上加用曲克芦丁注射液治疗。2组治疗14 d后(1个疗程)进行神经功能缺损评定,比较临床疗效,并观察不良反应。结果丹红治疗组总有效率76.7%,高于芦丁对照组的50.0%;治疗14 d后2组神经功能缺损评分均低于治疗前,且丹红治疗组低于芦丁对照组;差异均有统计学意义(P<0.05)。2组均未见严重不良反应。结论丹红注射液可有效改善临床症状,促进神经功能恢复,对于急性脑梗死的治疗能起到较好的辅助作用。
Objective To explore the clinical effect of Danhong injection in the treatment of acute cerebral infarction.Methods Using retrospective analysis,60 patients with cerebral infarction meeting the diagnostic criteria were randomly divided into Danhong injection treatment group(danhong treatment group)30 cases and troxerutin injection treatment group(rutin control group)30 cases.Both groups were given conventional treatment.Danhong treatment group was treated with Danhong injection on the basis of conventional treatment,and rutin control group was treated with trochortin injection on the basis of conventional treatment.After 14 days(1 course)of treatment in the two groups,neurological deficit assessment was performed,the clinical efficacy was compared,and adverse reactions were observed.Results The total effective rate of the Danhong treatment group was 76.7%,which was higher than the 50.0%of the rutin control group.After 14 days of treatment,the neurological deficit score of the two groups was lower than before the treatment,and the Danhong treatment group was lower than the rutin control group.There was statistical significance(P<0.05).No serious adverse reactions were seen in either group.Conclusion Danhong injection can effectively improve the clinical symptoms and promote the recovery of nerve function,and it can play a better auxiliary role in the treatment of acute cerebral infarction.
作者
涂锦可
王珊珊
TU Jinke;WANG Shanshan(Department of Pharmacy,Dongtong Hospital of Jiangxi Jiangtong Copper Group,Fuzhou 331812,China;Department of Hypertension,Henan Provincial People's Hospital,Zhengzhou 450003,China)
出处
《中国实用神经疾病杂志》
2020年第3期264-267,共4页
Chinese Journal of Practical Nervous Diseases
基金
河南省医学科技攻关项目(编号:201702177)。
关键词
脑梗死
缺血性脑卒中
脑血管疾病
丹红注射液
曲克芦丁注射液
Danhong injection
Ischemic stroke
Cerebrovascular disease
Cerebral infarction
Troxerutin injection