急性脑梗死患者脑动脉狭窄的分布及危险因素分析

Distribution and risk factors of cerebral artery stenosis in patients with acute cerebral infarction

目的分析急性脑梗死患者脑动脉狭窄的具体分布特点以及相关危险因素。方法选取焦作煤业集团中央医院2010-02—2017-02收治的516例急性脑梗死脑动脉狭窄患者为研究对象,所有患者经DSA(数字减影血管造影)证实,将其归为观察组,再选取同时期焦作煤业集团中央医院诊治的386例无脑动脉狭窄的脑梗死患者为对照组,分析观察组患者的脑动脉狭窄分布情况,同时对脑动脉狭窄形成的影响因素行单因素与多因素Logistic回归分析,明确影响脑动脉狭窄的相关危险因素。结果320例为单纯颅内动脉狭窄,构成比为62.0%;88例为单纯颅外动脉狭窄,构成比为17.1%;108例为颅内合并颅外动脉狭窄,构成比为20.9%。376例为前循环动脉狭窄,构成比为72.9%;140例为后循环动脉狭窄,构成比为27.1%。脑动脉狭窄以颅内动脉狭窄、前循环动脉狭窄为主。多因素Logistic回归分析显示,脑动脉狭窄形成的独立危险因素包括尿酸(UA)、收缩压、吸烟(P<0.05)。结论急性脑梗死患者脑动脉狭窄以颅内动脉狭窄、前循环动脉狭窄为主,UA、收缩压、吸烟为脑动脉狭窄形成的独立危险因素。

Objective To analyze the specific distribution characteristics and related risk factors of cerebral artery stenosis in patients with acute cerebral infarction.Methods 516 patients with acute cerebral infarction with cerebral artery stenosis were selected from the Central Hospital of Jiaozuo Coal Industry Group from February 2010 to February 2017.All patients were confirmed by DSA(digital subtraction angiography)and classified as observation group.386 patients with cerebral infarction without cerebral artery stenosis diagnosed and treated in the Central Hospital of Jiaozuo Coal Group were selected as the control group.The distribution of cerebral artery stenosis in the observation group was analyzed,and the factors affecting the formation of cerebral artery stenosis were single factor and more.Logistic regression analysis of factors identified the relevant risk factors affecting cerebral artery stenosis.Results 320 cases were simple intracranial artery stenosis(62.0%),88 cases were simple extracranial artery stenosis(17.1%),108 cases were intracranial combined extracranial artery stenosis(20.9%).376 cases were anterior circulation artery stenosis,with a composition ratio of 72.9%,and 140 cases were posterior circulation artery stenosis,with a composition ratio of 27.1%.Multivariate Logistic regression analysis showed that independent risk factors for cerebral artery stenosis included UA,systolic blood pressure and smoking(P<0.05).Conclusion Intracranial artery stenosis and anterior circulation artery stenosis were the main causes of cerebral artery stenosis in patients with acute cerebral infarction.UA,systolic blood pressure and smoking were independent risk factors for the formation of cerebral artery stenosis.