上皮性卵巢癌靶向治疗的研究进展

卵巢癌是严重影响女性健康的生殖系统三大恶性肿瘤之一,其中85%~90%属于上皮性卵巢癌。虽然卵巢癌发病率位于妇科恶性肿瘤第三位,但致死率却高居首位,其早期诊断困难、治疗后易复发及耐药性等特点仍然是治疗中需要突破的难题。随着近年来肿瘤研究及精准治疗的飞速发展,卵巢癌靶向治疗逐渐成为现阶段的研究热点。靶向治疗是以肿瘤细胞作为治疗靶点,对正常细胞影响较小,是一种理想的治疗方式,且靶向药物联合传统化疗药物可以有效缓解症状,缩短治疗疗程,进一步改善患者的生存质量。本文将就上皮性卵巢癌靶向治疗的相关研究进展进行综述。

Ovarian cancer is one of the three major malignant tumors of the reproductive system that seriously affect women's health,and 85%to 90%of them are epithelial ovarian cancer.Although the incidence of ovarian cancer is the third in gynecologic malignancies,but the mortality rate is the highest,it's difficult to diagnose early,easy to relapse after treatment and drug resistance is still a difficult problem in treatment.With the rapid development of tumor research and precision treatment in recent years,the targeted therapy of ovarian cancer has gradually become a research hotspot at present.Targeted therapy is an ideal treatment method which regards tumor cells as a therapeutic target,and has little effect on normal cells.And targeted drugs combined with traditional chemotherapy drugs can effectively alleviate symptoms,shorten the course of treatment,and further improve the quality of life of patients.This article reviews the research progress of targeted therapy for epithelial ovarian cancer.