反流性咳嗽的发病机制、诊断和治疗

The pathogenesis,diagnosis and treatment of gastroesophageal reflux related chronic cough

反流性咳嗽是胃食管反流病的常见食管外症状之一,其发生机制包括微吸入、咽喉反流和神经反射。目前可用的诊断方法包括质子泵抑制剂试验、排除呼吸道病因及寻找胃食管反流相关证据,治疗方法包括调整饮食和生活方式、药物治疗、内镜下射频治疗和腹腔镜下胃底折叠术。

Gastroesophageal reflux related chronic cough is one of the common extra-esophageal symptoms of gastroesophageal reflux disease,its potential mechanism are microaspiration,laryngopharyngeal reflux and esophageal-bronchial reflex.As for diagnosis,proton pump inhibitor trail,a clinical profile aimed at excluding other potential chronic cough causes and search for gastroesophageal reflux related evidence are worth of consideration.While its treatment options include diet and lifestyle modification,medication,radiofrequency therapy and laparoscopic fundoplication.