急性呼吸道感染患儿病原学分布及临床特点分析

Pathogenic distribution and clinical characteristics of children with acute respiratory tract infection

目的研究急性呼吸道感染(ARI)患儿病原体分布及临床特点。方法选择2018年1月至2019年5月安徽省宿州市立医院院新生儿科收治的ARI患儿85例为研究对象,观察患儿病原体分布、在不同年龄、季节检出病原体情况、临床特征。结果85例患儿中检出血清样本中IgM阳性35例,阳性率为41.18%;>20d且<28d患儿病原体IgM总阳性率高于≤20d(χ2=10.365,P=0.001);春、夏、秋、冬季节病原体IgM总阳性率分别为57.69%(15/26)、80.00%(20/25)、55.56%(10/18)、12.50%(2/16),差异有统计学意义(χ2=17.775,P=0.001);85例ARI患儿出现干咳50例占58.85%、咽部充血84例占98.82%、体温>38.5℃56例占65.88%、肺纹理粗乱伴有点片阴影61例占71.76%、白细胞>10.0×109/L65例占76.47%。结论MP为ARI患儿主要病原菌。其中年龄、季节为呼吸道病原体感染重要因素,且夏季为感染高发期。

Objective To investigate the distribution and clinical characteristics of pathogens in children with acute respiratory infection(ARI).Methods A total of 85 children with ARI in our hospital from January 2018 to May 2019 were enrolled.The distribution of pathogens,clinical characteristics,and the detection rate among different,ages,and seasons were observed.Results Among 85 children,35 cases(41.18%)were positive for serum IgM.The total positive rate of IgM among children aged between 20d and 28d was higher than those aged less than 20d(χ2=10.365,P=0.001).MP,RSV,INFB and PIV showed significant difference between two age groups(P<0.05).The total positive rates of IgM in spring,summer,autumn and winter were 57.69%(15/26)、80.00%(20/25)、55.56%(10/18)and 12.50%(2/16),respectively(χ2=17.775,P=0.001).The clinical characteristics of 85 cases of ARI included 50 cases(58.85%)of dry cough,84 cases(98.82%)of pharyngeal congestion,56 cases(71.76%)of body temperature>38.5℃(65.88%),61 cases of pulmonary texture disorder with spot shadow and 65 cases(76.47%)of white blood cells>10.0×109/L.Conclusion MP is the main pathogen in ARI children.age and season are important factors for respiratory tract pathogen infection,and summer is the peak period of infection.