清热排毒胶囊治疗湿热蕴结型急性痛风性关节炎临床观察

Clinical observation on treating acute gout of the Shire Yunjie type withthe Qingre Paidu capsule

目的:观察清热排毒胶囊治疗急性痛风的临床疗效。方法:将80例急性痛风患者采用随机数字表法随机分为两组。对照组急性期给予秋水仙碱1 mg(3次/d),口服至疼痛明显好转后停用,缓解期给予别嘌醇片50 mg(3次/d)口服治疗。治疗组西医治疗同对照组,同时全程加服清热排毒胶囊(萆薢、土茯苓、延胡索、没药、三七、秦艽、薏苡仁、黄芪、甘草),每次4粒,3次/d。疗程均为4周。观察两组临床疗效、急性复发例数,以及血尿酸的水平变化。结果:治疗组治愈20例,好转18例,未愈2例,有效率为95.00%(38/40)。对照组治愈16例,好转20例,未愈4例,有效率为90.00%(36/40)。两组对比,差异有统计学意义(P<0.01)。治疗后两组中医证候积分均显著降低(P<0.01),但两组间差异无统计学意义(P>0.05)。结论:清热排毒胶囊治疗急性痛风疗效显著。

Objective:To observe the clinical efficacy of the Qingre Paidu capsule(清热排毒胶囊)on acute gout.Methods:80 patients with acute gout were randomly divided into two groups by random number table method.The control group was given colchicine orally in the acute stage until the pain was significantly improved,and given allopurinol tablets orally during the remission phase.The treatment group was given the Qingre Paidu capsule more.Results:In the treatment group,20 cases were cured,18 cases were improved,and 2 cases were unhealed.The efficiency was 95.00%(38/40).In the control group,16 cases were cured,20 cases were improved,and 4 cases were unhealed.The efficiency was 90.00%(36/40).The difference between the two groups was statistically significant(P﹤0.01).After treatment,the TCM syndrome scores in two groups were significantly reduced(P﹤0.01),but there was no significant difference between the two groups(P﹥0.05).Conclusion:The Qingre Paidu capsule is effective on acute gout.