脑出血患者急性期凝血与纤溶功能的评估

Assessment of Coagulation and Fibrinolysis in Patients with Acute Cerebral hemorrhage

目的分析脑出血患者急性期凝血与纤溶功能情况。方法选择2017~2018年收治的50例脑出血急性期患者为研究对象,另取50例健康者为对照组,实施凝血与纤溶功能检查与分析。结果观察组患者在急性发病期中第1、3 d外周血小板数量明显降低,D-D上升(P<0.05),发病后7 d得以恢复。观察组病患者发病后3、7 d血浆Fbg、t-PA以及TAT明显上升(P<0.05),AT显著下降(P<0.05).结论脑出血病患在急性期内,会体现出凝血功能上调以及纤溶活性增强现象。故应当积极观察患者血小板、血浆D-D、血浆Fbg、TAT、AT以及t-PA等指标,并根据不同时期不同情况的改变予以调整。

Objective Analysis of acute stage clotting and fibrous function in patients with cerebral hemorrhage.Methods 50 patients admitted to the acute stage of cerebral hemorrhage in 2017-2018 were selected as the subjects,and 50 healthy patients were selected as control groups to carry out the examination and analysis of the function of clotting and fibula.Results The number of platelets in the 1 st and 3 d peripheral weeks in the acute stage of morbidity decreased significantly,D-D rose(P<0.05)and 7 d was restored after the onset.Patients with observational group of patients with 3,7 d plasma Fbg,t-PA and TAT increased significantly after the onset of the disease(P<0.05),and AT significantly decreased(P<0.05).Conclusion Cerebral hemorrhage patients in the acute period,will reflect the increased function of clotting and increased fibrous activity.Therefore,patients should actively observe the platelets,plasma D-D,plasma Fbg,TAT,AT and t-PA and other indicators,and adjust according to different periods of change.