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雾化吸入乙酰半胱氨酸溶液联合振动机械排痰治疗重型颅脑损伤后坠积性肺炎效果观察 被引量:36

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摘要 目的观察雾化吸入乙酰半胱氨酸溶液联合振动机械排痰治疗重型颅脑损伤后坠积性肺炎的临床效果。方法将120例重型颅脑损伤后坠积性肺炎患者随机分为三组各40例,A组行雾化吸入乙酰半胱氨酸溶液联合振动机械排痰治疗、B组行雾化吸入乙酰半胱氨酸溶液治疗、C组行振动机械排痰治疗,其余基础治疗措施均相同。三组治疗前及治疗3 d后行咳嗽、痰液量、痰液性状评分,记录发热、咳嗽、肺部啰音缓解时间及机械通气时间、住院时间,评价临床疗效。结果治疗前,三组咳痰评分差异均无统计学意义;治疗3 d后,A组咳嗽、痰液性状评分均低于B组和C组而痰液量评分高于B组和C组(P均<0.05),C组咳嗽评分低于B组而痰液量、痰液性状评分高于B组(P均<0.05)。治疗后,A组发热、咳嗽、肺部啰音缓解时间及机械通气时间、住院时间均短于B组和C组(P均<0.05),C组发热、咳嗽、肺部啰音缓解时间均短于B组(P均<0.05)。临床疗效显效率A组高于B组和C组(P均<0.05),B组和C组显效率比较差异无统计学意义(P>0.05)。结论重型颅脑损伤后坠积性肺炎应用雾化吸入乙酰半胱氨酸溶液联合振动机械排痰,可通过促进排痰改善患者的临床症状,并提高治疗效果。
出处 《山东医药》 CAS 2020年第11期62-64,共3页 Shandong Medical Journal
基金 河北省邢台市科技支撑计划项目(201609813)。
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