摘要
百日咳是由百日咳杆菌引起的急性呼吸系统传染病,传染性非常强,有较高的死亡率,是引起新生儿及婴儿死亡的重要原因.我国自1978年加入世界卫生组织扩大免疫规划策略,并将百日咳疫苗纳入国家计划免疫以来,百日咳的发病率明显下降.近年来,全球多个国家出现了百日咳发病的持续增高,局部地区还呈现爆发流行.该文就百日咳的流行病学、百日咳再现的原因展开综述,提高临床医生对百日咳的认识,对我国百日咳的防控提出建议.
Pertussis is a highly contagious respiratory tract infection caused by the Gram-negative bacterium Bordetella pertussis.It carries a significant incidence of fatality among newborn and infants.China has adopted the World Health Organization Expanded Programme on Immunization since 1978.Pertussis vaccine was included in the National Vaccine Program Schedule.The incidence of pertussis decreased significantly with the introduction of vaccine worldwide.Even though,pertussis also reappeared in countries with high vaccination coverage.Outbreaks of pertussis happened in some areas and countries worldwide.This article reviews the epidemiology and causal factors to increase awareness of the pertussis and make suggestions for the control and prevention of the pertussis in China.
作者
刘艳芹(综述)
于华凤
马香(审校)
Liu Yanqin;Yu Huafeng;Ma Xiang(Department of Respiratory,Qilu Children′s Hospital of Shandong University,Jinan 250022,China)
出处
《国际儿科学杂志》
2020年第2期91-95,共5页
International Journal of Pediatrics
基金
济南市临床科技创新计划(201805015,201907032)
济南市卫计委科技计划项目青年计划(2017-2-19)。
关键词
百日咳
重现
疫苗
流行病学
Pertussis
Resurgence
Vaccine
Epidemiology
