音乐游戏运动疗法对高龄轻度认知障碍患者干预效果的研究

Effect of Music Game Exercise Therapy on Elderly Patients with Mild Cognitive Impairment

目的探讨音乐游戏运动疗法对高龄轻度认知障碍(mild cognitive impairment,MCI)患者功能独立性的影响。方法纳入2017年1月-2018年12月于上海市普陀区人民医院老年科住院的60例65~95岁的MCI患者,随机分为观察组和对照组,观察组患者开展一周5次、每次40 min、持续6周的音乐游戏运动疗法,对照组采用常规健康教育。采用功能独立性评定量表(functional independence measure,FIM)对患者治疗前及治疗6周效果进行总体评价。结果观察组(30例,实际完成28例)与对照组(30例,实际完成30例)一般情况和治疗前FIM得分差异无统计学意义。治疗后观察组FIM中运动功能(P=0.006)、认知功能(P=0.001)和总分(P=0.001)优于对照组。观察组治疗后FIM中运动功能(P<0.001)、认知功能(P<0.001)和总分(P<0.001)均高于本组治疗前。对照组治疗后FIM得分与治疗前差异无统计学意义。结论音乐结合游戏运动疗法对高龄MCI患者是一项有效的非药物治疗方法,能延缓MCI进程,提高患者运动功能及认知功能。

Objective To investigate the effect of music game exercise therapy on functional independence in elderly patients with mild cognitive impairment(MCI).Methods Sixty elderly MCI patients at department of geriatrics of Shanghai Putuo people’s hospital from January 2017 to December 2018 were enrolled in this study.They were randomly divided into observation group and control group.The patients in observation group were treated with music game exercise therapy five times a week and 40 minutes each time for six weeks.The control group were given routine health education.The functional independence measure(FIM)was used to evaluate the effect of treatment before treatment and at six weeks after treatment.Results There was no significant difference in the general condition and FIM scores between observation group(n=30,actually complete:n=28)and control group(n=30,actually complete:n=30)before treatment.Motor function(P=0.006),cognitive function(P=0.001)and total score(P=0.001)of FIM in observation group were all better than that in control group after treatment.Motor function(P<0.001),cognitive function(P<0.001)and total score(P<0.001)of FIM in observation group after treatment were all better than before treatment.The total score of FIM in control group had no statistical difference before and after treatment.Conclusions Music combined with game exercise therapy is an effective non-drug therapy for elderly patients with MCI,which can delay the process of MCI and improve motor and cognitive function of elderly patients.