纳米金颗粒的晶种法制备及表征

Preparation and Characterization of Nano-gold Particles by Seeding Method

为研究纳米金颗粒制备工艺的均一性与稳定性,通过晶种生长法,以氯金酸为原料,以柠檬酸钠为保护剂,硼氢化钠为还原剂,用化学还原法制备尺寸为5 nm、10 nm、15 nm的单分散纳米金颗粒。以15 nm纳米金颗粒为初级晶种,以柠檬酸钠为保护剂,用抗坏血酸做还原剂,通过改变氯金酸与晶种的用量,制备不同粒径纳米金颗粒。通过透射电镜和紫外-可见分光光度计对不同粒径的纳米金颗粒进行表征。结果显示,通过晶种法成功制备了粒径为40 nm、60 nm、80 nm、100 nm、150 nm和200 nm的纳米金颗粒,颗粒均一,分散性好,无明显团聚现象。结果表明,晶种法制备的纳米金颗粒粒径均一,质量稳定。

In order to study the homogeneity and stability of preparing nano-gold particles,a series of nano-gold particles with sizes of 5 nm,10 nm and 15 nm were preliminary prepared by chemical reduction and seed-induced growth methods.This step was applied by using chloroauric acid as raw material,sodium citrate as protective agent and sodium borohydride as reducing agent.Then,nano-gold particles with different sizes were prepared by seeding method,15 nm nano-gold particles were used as the primary seeding crystal,sodium citrate was used as the protective agent,and ascorbic acid was used as the reducing agent,the using quantity of chloroauric acid and seeding crystal are adjustable parameters.The prepared particles were subsequently characterized by transmission electron microscopy and ultraviolet-visible spectrophotometer.The results showed that nano-gold particles with particle diameters of 40 nm,60 nm,80 nm,100 nm,150 nm and 200 nm were successfully prepared.Moreover,the particles have uniform particle size,good dispersibility and no obvious agglomeration.In conclusion,nano-gold particles prepared by seeding method have uniform particle size and stable quality.