配体促进的过渡金属催化芳烃远程meta-C—H键官能化反应研究进展

Recent Advances in Ligand-Promoted Transition-Metal-Catalyzed Remote meta-C—H Functionalization of Arenes

过渡金属催化C—H活化反应中,配体能够对催化中心的空间及电子效应进行调控,从而实现芳烃C—H键的选择性官能化.近年来,配体促进芳烃远程C—H键官能化反应研究有了新的进展.对近几年来配体促进的过渡金属催化芳烃远程meta-C—H键选择性官能化反应进行了系统总结,并对该研究领域的局限性和未来的发展前景进行总结和展望.

Ligands can regulate both the steric and electronic effects of the catalytic center in transition-metal-catalyzed C—H activation reactions,leading to the site-selective C—H functionalization of arenes.In recent years,ligand-promoted remote C—H functionalization of arenes has developed rapidly.The recent progress on ligand-promoted transition-metal-catalyzed remote meta-selective C一H bond functionalization of arenes is summarized,and the limitations of the research field and prospects for future development are presented.