比阿培南延长输注治疗ICU患者重症感染的临床疗效

Clinical Effect of Prolonging Infusion Time of Biapenem in Treatment of Severe Infection in Patients in ICU

目的 研究分析ICU重症感染患者通过延长比阿培南输注时间治疗的临床价值.方法 选取2017年8月至2019年4月百色市人民医院收治的ICU的患者80例,将其分为对照组与40例,行30?min常规治疗,实验组40例行延长2?h比阿培南输注时间治疗,比较2组的临床价值.结果 (1)2组的细菌清除率经比较差异无统计学意义(P>0.05).(2)对照组总有效率为70.00%,低于观察组的92.50%(P<0.05);(3)2组输注用药疗程的对比后差异无统计学意义(P>0.05).(4)2组的不良反应经比较差异无统计学意义(P>0.05).结论 ICU重症感染患者通过延长比阿培南输注时间治疗效果显著.

Objective To study and analyze the clinical value of prolonging the infusion time of biapenem in patients with severe infection in ICU.Methods Eighty patients in ICU treated in our hospital from August 2017 to April 2019 were divided into control group(n=40)and experimental group(n=40).The control group was treated with routine treatment for 30 minutes,and the experimental group was treated with extended infusion time of biapenem for 2 h.The clinical value of the two groups was compared.Results(1)No difference was found in the bacterial clearance rate between the two groups(P>0.05).(2)The total effective rate in the control group was 70.00%,which was lower than 92.50%in the observation group,and the difference was significant(P<0.05);(3)No difference was found between the two groups after the administration time(P>0.05).(4)After comparing the adverse reactions of the two groups,no difference was found(P>0.05).Conclusion The treatment effect of ICU patients with severe infection by prolonging the infusion time of apenem is significant.