探讨肠道益生菌联合小儿腹泻贴治疗小儿腹泻的效果及对炎性因子水平的影响

To Investigate the Effect of Intestinal Probiotics Combined with Pediatric Diarrhea Patch on Pediatric Diarrhea and Its Effect on Inflammatory Factor Levels

目的 探讨肠道益生菌联合小儿腹泻贴治疗小儿腹泻的效果及对炎性因子水平的影响.方法 选取2018年4月至2019年9月辛集市第一医院收治的62例小儿腹泻患儿,将所有患儿随机编号(1~62号),其中1~31号为对照组采取肠道益生菌治疗, 32~62号为研究组给予肠道益生菌联合小儿腹泻贴治疗,对比治疗效果、炎性因子水平.结果 研究组临床总有效率93.55%,显著高于对照组(74.19%,P<0.05);治疗前,2组白细胞介素-6、白细胞介素-10、肿瘤坏死因子等炎性因子水平比较,差异无统计学意义(P>0.05);治疗后,2组炎性因子水平均有所降低,但是,研究组降低幅度更加明显,组间差异显著(P<0.05).结论 给予小儿腹泻患儿肠道益生菌联合小儿腹泻贴治疗,临床治疗效果显著,能够最大限度改善机体炎性因子水平,促进患儿康复.

Objective To investigate the effect of intestinal probiotics combined with pediatric diarrhea patch on pediatric diarrhea and its effect on inflammatory factor levels.Methods A total of 62 children with diarrhea admitted to the first hospital of Xinji city from April 2018 to September 2019 were randomly numbered(No.1~62),among which No.1~31 was the control group and No.32~62 was the study group.The treatment effect and inflammatory factor level were compared.Results The total clinical effective rate of the study group was 93.55%,significantly higher than that of the control group(74.19%,P<0.05).Before treatment,there was no significant difference in the levels of IL-6,IL-10 and TNF between the two groups(P>0.05).After treatment,the level of inflammatory factors in the two groups were reduced,but the reduction of the study group was more significant,the difference between the groups was significant(P<0.05).Conclusion The treatment of children diarrhea with intestinal probiotics combined with children diarrhea patch can improve the level of inflammatory factors and promote the recovery of children.