美托洛尔与卡维地洛治疗心室收缩不同步特发性扩张型心肌病的疗效对比

Comparison of Effect of Metoprolol and Carvedilol in Treatment of Ventricular Systolic Asynchrony Idiopathic Dilated Cardiomyopathy

目的探讨不同β-受体阻滞剂用于心室收缩不同步特发性扩张型心肌病(IDC)中的治疗价值.方法选取2017年1月至2018年6月重庆市长寿区人民医院收治的80例IDC患者,随机均分为两组,各40例.对照组选用美托洛尔,观察组选用卡维地洛,治疗6个月后观察疗效.结果观察组治疗总有效率高于对照组(P<0.05);观察组心电图(QRS)波宽低于对照组(P<0.05);观察组不良反应发生率低于对照组(P<0.05).结论选用卡维地洛可以提升疗效、纠正心室收缩不同步并减少不良反应.

Objective To investigate the therapeutic value of different beta-blockers in patients with ventricular systolic dyssynchrony idiopathic dilated cardiomyopathy(IDC).Methods Eighty IDC patients admitted People's Hospital of Changshou Chongqing from January 2017 to June 2018 were randomly divided into two groups,40 cases in each group.Metoprolol was used in the control group and carvedilol was used in the observation group.The curative effect was observed after 6 months of treatment.Results The total effective rate in the observation group was higher than that in the control group(P<0.05).The QRS width in the observation group was smaller than that in the control group(P<0.05).The incidence of adverse reactions in the observation group was lower than that in the control group(P<0.05).Conclusion Carvedilol can be used to improve the efficacy,correct ventricular dyssynchrony and reduce adverse reactions.