脑室腹腔分流术对重症结核性脑膜炎合并脑积水的治疗效果及并发症、生活质量评分分析

Effect of Ventriculoperitoneal Shunt on Severe Tuberculous Meningitis with Hydrocephalus and Analysis of Complications and Quality of Life Score

目的分析脑室腹腔分流术对重症结核性脑膜炎合并脑积水的治疗效果及并发症、生活质量评分.方法选取2015年5月至2018年5月中国人民解放军第九〇四医院收治的重症结核性脑膜炎合并脑积水患者40例作为研究对象,均实施脑室腹腔分流术治疗,比较治疗前后颅压、脑室体部宽度指数、脑脊液参数、生活质量,并统计治疗的总有效率与并发症发生情况.结果治疗后颅压、脑室体部宽度指数、脑脊液参数明显优于治疗前(P<0.05);治疗后,生活质量评分明显高于治疗前(P<0.05).术后一年,患者治疗总有效率为65.00%(26/40).结论脑室腹腔分流术用于重症结核性脑膜炎合并脑积水患者临床疗效较好,并可改善患者生活质量.

Objective To analyze the therapeutic effect,complications and quality of life score of ventriculoperitoneal shunt on severe tuberculous meningitis with hydrocephalus.Methods Forty patients with severe tuberculous meningitis with hydrocephalus admitted to the 904 hospital of the Chinese People's Liberation Army from May 2015 to May 2018 were selected as the study subjects and were treated with ventriculoperitoneal shunt.The intracranial pressure,ventricular body width index,cerebrospinal fluid parameters and quality of life were compared before and after treatment.The total effective rate and the incidence of complications were summarized.Results The intracranial pressure,ventricular body width index and cerebrospinal fluid parameters after treatment were significantly better than those before treatment(P<0.05).After treatment,the quality of life score was significantly higher than that before treatment(P<0.05).One year after operation,the total effective rate was 65%(26/40).Conclusion Ventriculoperitoneal shunt on severe tuberculous meningitis with hydrocephalus was effective and can improve the quality of life of patients.