血清心肌坏死标志物检测在急性心肌梗死早期诊断中的应用分析

Application of Serum Myocardial Necrosis Markers in Early Diagnosis of Acute Myocardial Infarction

目的分析血清心肌坏死标志物检测在急性心肌梗死早期诊断中的应用价值.方法选取江苏省启东市第三人民医院2016年1月至2018年12月收治的136例急性心肌梗死患者作为本次实验的研究组,另选择同一时期疑似早期急性心肌梗死且最后排除的136例患者为对照组,分别检测两组患者肌酸激酶(CK)、肌酸激酶同工酶(CK-MB)、肌钙蛋白Ⅰ(cTnⅠ)以及肌红蛋白(MYO)含量,并分析检测结果.结果研究组患者CK、CK-MB、MYO以及cTnⅠ含量明显高于对照组,且差异有统计学意义(P<0.05);患者在发生急性心肌梗死后,MYO含量会明显升高,并在发病后12h达到峰值,cTnⅠ在发病后2~6h内不断升高,且在发病后12h达到峰值.结论血清心肌坏死标志物检测在急性心肌梗死早期诊断的应用价值较高.

Objective To analyze the application value of serum myocardial necrosis markers in early diagnosis of acute myocardial infarction.Methods Totally 136 and thirty-six patients with AMI admitted to Qidong Third People's Hospital of Jiangsu Province from January 2016 to December 2018 were selected as the study objects,and 136 patients suspected of AMI in the same period and finally excluded were used as the control.Creatine kinase(CK),creatine kinase isoenzyme(CK-MB,CTN),troponin I(cTnI)and myo redmyoglobin(MYO)were detected in the two groups respectively The content of protein(myo)was,and the results were analyzed.Results The contents of CK,CK-MB,myoMYO and CTNⅠcTNI in the study group were significantly higher than those in the control group(P<0.05).After acute myocardial infarction,the content of myoMYO will increase significantly,and the peak value will be developed at 12 h 12 h after the onset of the disease.CTNⅠcTNI will continue to increase within 2-6 h 6 h after the onset of the disease,and reach the peak value at 12 h after the onset of the disease.Conclusion The detection of serum myocardial necrosis markers has a high value in the early diagnosis of acute myocardial infarction.