动态CT多期增强特点与前列腺癌血清前列腺特异性抗原及碱性磷酸酶的相关性研究

Correlation Between Multi-phase Enhancement of Dynamic CT and Serum Prostate Specific Antigen and Alkaline Phosphatase in Prostate Cancer

目的探讨动态CT多期增强特点与前列腺癌血清前列腺特异性抗原(PSA)及碱性磷酸酶(ALP)的相关性研究.方法选取北京中医药大学房山医院医学影像中心2016年1月至2018年12月收治的50例前列腺癌患者作为观察组,同时选取50例健康老年人为对照组.检测两组动态CT多期增强特点(CT最大净增值)和外周血中PSA和ALP的表达差异.结果观察组PSA水平和ALP的水平显著高于对照组(P<0.05);观察组的动态CT多期增强特点(CT最大净增值)明显升高(P<0.05).Pearson相关性分析结果显示,PSA水平和ALP的水平与动态CT多期增强特点(CT最大净增值)呈正相关(P<0.05).结论动态CT多期增强特点与前列腺癌血清PSA及ALP密切相关.

objective To investigate the correlation between dynamic CT multiphase enhancement and serum prostatespecific antigen(PSA)and alkaline phosphatase(ALP)in prostate cancer.Methods Totaiiy 50 patients with prostate cancer admitted to our hospital from January 2016 to December 2018 were selected as the observation group,and 50 healthy elderly patients were selected as the control group.The dynamic CT multiphase enhancement characteristics(maximum net increase of CT)and the expression differences of PSA and ALP in peripheral blood were detected and compared between the observation group and the control group.Results PSA and ALP levels in the observation group were significantly higher than those in the control group(P<0.05).Dynamic CT multiphase enhancement(maximum net increase)was significantly increased in the observation group(P<0.05).Pearson correlation analysis showed that PSA and ALP levels were positively correlated with dynamic CT multiphase enhancement(maximum net increase in CT value)(P<0.05).Conclusion Dynamic CT multiphase enhancement is closely related to PSA and ALP in prostate cancer.