超声引导病变部位冲击波对肩周炎患者TNF-α、IL-6的影响

Effect of Ultrasound-Guided Shock Wave on TNF-αand IL-6 in Patients with Periarthritis

目的 探讨超声引导病变部位冲击波对肩周炎患者肿瘤坏死因子-α(TNF-α)、白介素-6(IL-6)的影响.方法 回顾性分析2017年8月至2019年5月在徐州医科大学附属沭阳医院诊治的26例肩周炎患者,采用超声引导下病变部位冲击波治疗,共治疗2周.分析治疗前后视觉模拟评分(VAS)及肩关节(Constant-Murley)评分;血清TNF-α、IL-6水平以及治疗4周后的病灶超声表现情况.结果 与治疗前相比,治疗4周后VAS评分均降低,Constant-Murley评分均升高(P<0.05);与治疗前相比,治疗4周后血清TNF-α、IL-6水平均降低;治疗4周后超声扫查病灶部位,发现4处钙化灶均有缩小,19处液性暗区有8处消失,10处缩小,6处肩袖撕裂无明显改善.结论 超声可清晰显示肩周炎的病变部位,针对病变部位进行治疗,可抑制炎症反应,减轻疼痛程度,改善肩关节功能.

Objective To investigate the effect of ultrasound-guided shock wave on TNF-αand IL-6 in patients with scapulohumeral periarthritis.Methods A retrospective analysis was performed on 26 patients with periarthritis of shoulder diagnosed and treated in the shuyang hospital affiliated to xuzhou medical university from August 2017 to May 2019,who were treated with ultrasound-guided shock wave at the lesion site for a total of 2 weeks.VAS score and constant-murley score before and after treatment were analyzed.Serum levels of TNF--and il-6 as well as the sonographic findings of the lesions after 4 weeks of treatment.Results Compared with before treatment,the VAS scores reduced after 4 weeks of treatment,and the Constant-Murley scores increased(P<0.05).Compared with before treatment,serum TNF-αand IL-6 levels decreased after 4 weeks of treatment;After 4 weeks of treatment,the lesions were scanned by ultrasound and found that the calcifications were reduced in 4 locations,8 in 19 dark areas of fluid disappeared,10 were reduced,and 6 rotator cuff tears were not significantly improved.Conclusion Ultrasound can clearly show the pathological location of scapulohumeral periarthritis,and the treatment for the pathological location can obtain good clinical effect.