屏障环境的哨兵动物应用

Application of Sentinel Animals in Barrier Environment

屏障环境哨兵动物设置除考虑哨兵动物种属、品系、性别、周龄、数量、接触方式、放置位置、检测频次外,也要考虑排除动物受到的应激对监测结果干扰.依据实验动物“3R原则”,哨兵动物既可作微生物监测的指示动物,又可用于饲料营养的监测,提出设置哨兵动物数即实际检测哨兵动物数.

Sentinel animals in barrier environment should not only take into account the species,strain,sex,age,quantity,contact mode,placement position and detection frequency,but also the elimination of interference of animal stress on the monitoring results.Aaccording to the 3R theory of laboratory animals,make full use of sentinel animals as feed nutrition monitoring sentinel animals,put forward to set up the number of sentinel animals,that is the actual detection number of sentinel animals.