乳腺癌患者精神心理状态与症状困扰的相关性分析

Correlation analysis between mental health and symptom distress in breast cancer patients

目的探讨乳腺癌患者精神心理状态与症状困扰的相关性。方法收集2017年6月至2018年3月山西白求恩医院收治的110例女性乳腺癌患者的一般资料,对患者的症状困扰评估采用抑郁自评量表(SDS),精神心理评估采用乳腺癌患者生命质量测定量表(FACT-B)和慢性疾病治疗功能评估-灵性量表(FACIT-SP);应用多重线性回归分析患者的症状困扰对其精神心理健康的影响。结果所有患者症状困扰得分为(19.94±5.78)分,精神心理健康得分为(50.68±10.64)分,其中FACT-B得分为(16.85±4.75)分,FACIT-SP得分为(33.83±8.33)分。多因素分析显示,与症状困扰得分≤18分患者相比,得分>18分患者的精神心理健康得分降低了5.15分(P=0.01);与家庭年收入<5.0万元患者相比,家庭年收入为(5.0~7.9)万元患者的精神健康得分增加了9.46分(P<0.01),家庭年收入≥8.0万元患者的精神健康得分增加了5.92分(P<0.01);与肿瘤分期Ⅰ期患者相比,Ⅱ期患者的精神心理健康得分降低了2.62分(P=0.02),Ⅲ期患者的精神心理健康得分降低了4.98分(P<0.01)。结论症状困扰是影响乳腺癌患者精神心理健康的独立危险因素,通过解决患者的症状困扰,可改善其精神心理健康状态。

Objective To investigate the correlation between mental health and symptom distress in breast cancer patients.Methods The clinical data of 110 female breast cancer patients at Shanxi Bethune Hospital from June 2017 to March 2018 were collected.The patients were assessed for symptomatic distress with depression self-rating scale(SDS).Functional assessment of cancer therapy-breast(FACT-B)and the functional assessment of chronic illness therapy-spiritual well-being(FACIT-SP)were used to make the mental assessment.Multiple linear regression analysis was used to analyze the effect of symptom distress on the mental health of the patients.Results The scores of symptom distress,mental health,FACT-B and FACIT-SP were(19.94±5.78),(50.68±10.64),(16.85±4.75),(33.83±8.33),respectively.Multivariate analysis showed that mental health score of the patients with symptom distress>18 scores was reduced by 5.15 points(P=0.01)compared with the patients with symptom distress≤18 scores.Compared with the patients with annual household income<50000 yuan,the mental health score of patients with annual household income of 50000-79000 yuan was increased by 9.46 points(P<0.01),and the mental health score of patients with annual family income≥80000 yuan was increased by 5.92 points(P<0.01);compared with the patients in phase I,the mental health score of the patients in phaseⅡwas decreased by 2.62 points(P=0.02),and the mental health score of the patients in phaseⅢwas decreased by 4.98 points(P<0.01).Conclusions Symptom distress is an independent risk factor for affecting mental health of breast cancer patients.Solving symptom distress of patients can improve mental health status of the patients.