FFR阳性值小于0.71冠心病患者介入治疗的预后

The prognosis of interventional therapy in CHD patients with FFR value less than 0.71

目的评估冠状动脉粥样硬化性心脏病(冠心病)介入治疗中血流储备分数(FFR)小于0.71患者的预后。方法纳入于北京大学首钢医院行介入治疗且FFR测定≤0.8的60例冠心病患者。根据FFR值分为两组:试验组(FFR值≤0.71),24例;对照组(0.71<FFR值≤0.8),36例。两组患者均给予经皮冠状动脉介入治疗(PCI),随访1年,比较两组之间主要不良心血管事件(MACE)的发生率。结果两组患者基础资料无差异,在冠状动脉介入治疗情况以及术后用药情况方面无差异(P>0.05),术后1年内再次血运重建、急性心肌梗死、死亡、再发心绞痛等方面无明显差异(P>0.05),而试验组患者(37.5%)在总的主要不良心血管事件(MACE)发生率高于对照组(8.3%),差异具有显著统计学意义(P<0.01)。结论冠心病患者介入治疗中FFR≤0.71的患者预后更差。

Objective To evaluate the prognosis of patients with coronary heart disease and Fractional Flow reserve(FFR)value less than 0.71 in Percutaneous Coronary Intervention(PCI).Methods 60 patients with coronary atherosclerotic heart disease(coronary heart disease)who received interventional treatment at Peking University Shougang Hospital and whose FFR was≤0.8 were divided into two groups according to the FFR value,including the experimental group(FFR value≤0.71,24 cases)and control group(0.71<FFR value≤0.8,36 cases).Patients in both groups were given percutaneous coronary intervention(PCI)and followed up for 1 year.The incidence of major adverse cardiovascular events(MACE)was compared between the two groups.Results There was no difference in basic data between the two groups of patients.There was no difference in the status of coronary interventional therapy and postoperative medication(P>0.05).There was no significant difference in revascularization,acute myocardial infarction,death,and recurrent angina within 1 year after operation(P>0.05).The total incidence of major adverse cardiovascular events(MACE)in patients in the test group(37.5%)was higher than that in the control group(8.3%),and the difference was statistically significant(P<0.01).Conclusions Patients with coronary heart disease have a worse prognosis in patients with FFR≤0.71 during interventional therapy.