胸部CT联合血清中PCT、SAA水平检测对社区获得性肺炎病情的评价价值

The Value of Chest CT Combined with Detection of PCT and SAA Levels in Serum for the Evaluation on Conditions of Community Acquired Pneumonia

目的:分析胸部CT联合血清中PCT、SAA水平检测对社区获得性肺炎病情的评价价值。方法:选择北京市西城区广外医院收治的86例社区获得性肺炎患者作为研究对象。对患者行肺炎严重度指数(PSI)评分并分为PSI低危组、中危组及高危组。选择同期我院86例健康体检者作为对照组。对入组研究者进行胸部CT检查、血清降钙素(PCT)、淀粉样蛋白A(SAA)水平检测。比较两组患者胸部CT评分、PCT、SAA水平的差异。以患者病情预后分为生存组、死亡组,比较两组患者胸部CT评分、PCT、SAA水平情况。结果:社区获得性肺炎患者CT评分、PCT、SAA水平高于对照组(P<0.05);社区获得性肺炎PSI高危组患者CT评分、PCT、SAA水平高于PSI中危组、PSI低危组(P<0.05);社区获得性肺炎PSI中危组患者CT评分、PCT、SAA水平高于PSI低危组(P<0.05);社区获得性肺炎死亡组患者CT评分、PCT、SAA水平高于生存组(P<0.05)。结论:社区获得性肺炎患者PSI评分越高,病情越重,CT评分、PCT、SAA水平也越高,对患者临床预后也具有较高的指导价值。

Objective:To evaluate the value of PCT and SAA in Serum Combined with Chest CT in Evaluating Community Acquired Pneumonia.Methods:We selected 86 patients with community-acquired pneumonia admitted to our hospital from January 2016 to September 2017.The patients were screened for pneumonia severity index(PSI)and divided into low-risk PSI group,moderate-risk group and high-risk group.Select the same period in our hospital 86 cases of healthy people as a control group.Thoracic CT examination,serum calcitonin(PCT)and amyloid A(SAA)levels were performed on the participants.The differences of chest CT score,PCT and SAA between the two groups were compared.The prognosis of patients was divided into survival group and death group.CT scores of thorax,PCT and SAA in both groups were compared.Results:The CT score,PCT,SAA level of patients with community-acquired pneumonia were significantly higher than those of the control group,compared with the statistical difference(P<0.05).The scores of CT,PCT and SAA in PSI high risk group were significantly higher than those in PSI moderate risk group and PSI low risk group,compared with the statistical difference(P<0.05).The CT score,PCT and SAA level in patients with PSI in the community-acquired pneumonia group were higher than those in the low-risk PSI group,compared with the statistical difference(P<0.05).The CT score,PCT,SAA level in community-acquired pneumonia death group were significantly higher than those in survival group,compared with the statistical difference(P<0.05).Conclusion:Community-acquired pneumonia in patients with higher PSI scores,the more severe the disease,CT score,PCT,SAA levels were also higher,the clinical prognosis of patients also has a higher guiding value.